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1

The effects of theanine, as a novel biochemical modulator, on the antitumor activity of adriamycin

Yasuyuki Sadzuka, Tomomi Sugiyama, Atsuo Miyagishima, Yasuo Nozawa, Sadao Hirota

Journal:

Year:

1996

Language:

english

File:

PDF, 884 KB

english, 1996

2

Preparation and dissolution characteristics of griseofulvin solid dispersions with saccharides

Masataka Saito, Takashi Ugajin, Yasuo Nozawa, Yasuyuki Sadzuka, Atsuo Miyagishima, Takashi Sonobe

Journal:

International Journal of Pharmaceutics

Year:

2002

Language:

english

File:

PDF, 339 KB

english, 2002

3

The effect of caffeine on adriamycin efflux in Ehrlich ascites carcinoma cells.

Sadzuka, Yasuyuki, Iwazaki, Ayano, Miyagishima, Atsuo, Nozawa, Yasuo, Hirota, Sadao

Journal:

Drug Delivery System

Year:

1996

Language:

english

File:

PDF, 1.05 MB

english, 1996

4

Anti-neovascular therapy by liposomal drug targeted to membrane type-1 matrix metalloproteinase

Masami Kondo, Tomohiro Asai, Yasufumi Katanasaka, Yasuyuki Sadzuka, Hideo Tsukada, Koichi Ogino, Takao Taki, Kazuhiko Baba, Naoto Oku

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 523 KB

english, 2004

5

A dosage design of mitomycin C tablets containing finely powdered green tea

Takurou Kurita, Atsuo Miyagishima, Yasuo Nozawa, Yasuyuki Sadzuka, Takashi Sonobe

Journal:

International Journal of Pharmaceutics

Year:

2004

Language:

english

File:

PDF, 110 KB

english, 2004

6

Glycerin fatty acid esters as a new lubricant of tablets

Hiroyuki Aoshima, Atsuo Miyagisnima, Yasuo Nozawa, Yasuyuki Sadzuka, Takashi Sonobe

Journal:

International Journal of Pharmaceutics

Year:

2005

Language:

english

File:

PDF, 256 KB

english, 2005

7

Characterization and cytotoxicity of mixed polyethyleneglycol modified liposomes containing doxorubicin

Yasuyuki Sadzuka, Ikumi Sugiyama, Tomoko Tsuruda, Takashi Sonobe

Journal:

International Journal of Pharmaceutics

Year:

2006

Language:

english

File:

PDF, 205 KB

english, 2006

8

Study on liposomalization of zinc-coproporphyrin I as a novel drug in photodynamic therapy

Yasuyuki Sadzuka, Fumiaki Iwasaki, Ikumi Sugiyama, Kentaro Horiuchi, Toru Hirano, Hidechika Ozawa, Naohiro Kanayama, Takashi Sonobe

Journal:

International Journal of Pharmaceutics

Year:

2007

Language:

english

File:

PDF, 168 KB

english, 2007

9

Screening of biochemical modulator by tumor cell permeability of doxorubicin

Yasuyuki Sadzuka, Haruna Hatakeyama, Takashi Daimon, Takashi Sonobe

Journal:

International Journal of Pharmaceutics

Year:

2008

Language:

english

File:

PDF, 584 KB

english, 2008

10

Influence of load on particle size distribution of lactose–crystalline cellulose mixed powder

Takahiko Nakamori, Atsuo Miyagishim, Yasuo Nozawa, Yasuyuki Sadzuka, Takashi Sonobe

Journal:

International Journal of Pharmaceutics

Year:

2008

Language:

english

File:

PDF, 337 KB

english, 2008

11

A liposomal formulation study of 2,7-dichlorodihydrofluorescein for detection of reactive oxygen species

Yasuyuki Sadzuka, Kouhei Nakagawa, Hisashi Yoshioka, Takashi Sonobe

Journal:

International Journal of Pharmaceutics

Year:

2008

Language:

english

File:

PDF, 2.06 MB

english, 2008

12

Novel method for stratum corneum pore size determination using positron annihilation lifetime spectroscopy

Yoshiaki Itoh, Akira Shimazu, Yasuyuki Sadzuka, Takashi Sonobe, Shigeru Itai

Journal:

International Journal of Pharmaceutics

Year:

2008

Language:

english

File:

PDF, 380 KB

english, 2008

13

Effect of hybridized liposome by novel modification with some polyethyleneglycol-lipids

Ikumi Sugiyama, Takashi Sonobe, Yasuyuki Sadzuka

Journal:

International Journal of Pharmaceutics

Year:

2009

Language:

english

File:

PDF, 299 KB

english, 2009

14

Enhancement of doxorubicin concentration in the M5076 ovarian sarcoma cells by cucurbitacin E co-treatment

Yasuyuki Sadzuka, Haruna Hatakeyama, Takashi Sonobe

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 549 KB

english, 2010

15

Effects of mixed polyethyleneglycol modification on fixed aqueous layer thickness and antitumor activity of doxorubicin containing liposome

Yasuyuki Sadzuka, Akiko Nakade, Rieko Hirama, Atsuo Miyagishima, Yasuo Nozawa, Sadao Hirota, Takashi Sonobe

Journal:

International Journal of Pharmaceutics

Year:

2002

Language:

english

File:

PDF, 237 KB

english, 2002

16

Relationships between the in vitro cytotoxicity and transport characteristics of pirarubicin and doxorubicin in M5076 ovarian sarcoma cells, and comparison with those in Ehrlich ascites carcinoma cells

Katsuhito Nagai, Kazuki Nagasawa, Yasuyuki Sadzuka, Masayuki Tsujimoto, Kohji Takara, Noriaki Ohnishi, Teruyoshi Yokoyama, Sadaki Fujimoto

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 142 KB

english, 2002

17

Liposomalization of hydroxyphenyl fluorescein as a reagent for detecting highly reactive oxygen species

Ikumi Sugiyama, Saki Kojima, Naoto Oku, Yasuyuki Sadzuka

Journal:

Colloid & Polymer Science

Year:

2010

Language:

english

File:

PDF, 252 KB

english, 2010

18

Caffeine Modulates the Antitumor Activity and Toxic Side Effects of Adriamycin

Yasuyuki Sadzuka, Eiko Mochizuki, Yoshio Takino

Journal:

Year:

1993

File:

PDF, 364 KB

1993

19

Effects of Methylxanthine Derivatives on Adriamycin Concentration and Antitumor Activity

Yasuyuki Sadzuka, Ayano Iwazaki, Atsuo Miyagishima, Yasuo Nozawa, Sadao Hirota

Journal:

Year:

1995

File:

PDF, 404 KB

1995

20

Effect of CPT-11 on Lipid Peroxide Level in Mouse Tissues

Yasuyuki Sadzuka, Sadao Hirota

Journal:

Year:

1997

File:

PDF, 262 KB

1997

21

1-Methyl-3-propyl-7-butylxanthine, a Novel Biochemical Modulator, Enhances Therapeutic Efficacy of Adriamycin

Yasuyuki Sadzuka, Ayano Iwazaki, Tomomi Sugiyama, Takayuki Sawanishi, Ken-ichi Miyamoto

Journal:

Year:

1998

Language:

english

File:

PDF, 73 KB

english, 1998

22

Membrane Transport and Antitumor Activity of Pirarubicin, and Comparison with Those of Doxorubicin

Tomomi Sugiyama, Yasuyuki Sadzuka, Kazuki Nagasawa, Noriaki Ohnishi, Teruyoshi Yokoyama, Takashi Sonobe

Journal:

Year:

1999

Language:

english

File:

PDF, 95 KB

english, 1999

23

Effects of 1-Methyl-3-propyl-7-butylxanthine (MPBX) on Idarubicin-induced Antitumor Activity and Bone Marrow Suppression

Yasuyuki Sadzuka, Youichi Egawa, Tomomi Sugiyama, Hiroyuki Sawanishi, Ken-ichi Miyamoto, Takashi Sonobe

Journal:

Year:

2000

Language:

english

File:

PDF, 90 KB

english, 2000

24

Beneficial effects of curcumin on antitumor activity and adverse reactions of doxorubicin

Yasuyuki Sadzuka, Makiko Nagamine, Tatsushi Toyooka, Yuko Ibuki, Takashi Sonobe

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 1.17 MB

english, 2012

25

Effect of the physicochemical properties of initially injected liposomes on the clearance of subsequently injected PEGylated liposomes in mice

Tatsuhiro Ishida, Takako Ichikawa, Masako Ichihara, Yasuyuki Sadzuka, Hiroshi Kiwada

Journal:

Journal of Controlled Release

Year:

2004

Language:

english

File:

PDF, 221 KB

english, 2004

26

Anti-neovascular therapy by use of tumor neovasculature-targeted long-circulating liposome

Noriyuki Maeda, Yoshito Takeuchi, Miki Takada, Yasuyuki Sadzuka, Yukihiro Namba, Naoto Oku

Journal:

Journal of Controlled Release

Year:

2004

Language:

english

File:

PDF, 274 KB

english, 2004

27

Liposomalization of SN-38 as active metabolite of CPT-11

Yasuyuki Sadzuka, Hiroyuki Takabe, Takashi Sonobe

Journal:

Journal of Controlled Release

Year:

2005

Language:

english

File:

PDF, 142 KB

english, 2005

28

Mechanical complex formation of tolbutamide with β-cyclodextrin by solid phase roll mixing

Yasuo Nozawa, Hideki Nawa, Yasuyuki Sadzuka, Atsuo Miyagishima, Sadao Hirota

Journal:

Pharmaceutica Acta Helvetiae

Year:

1997

Language:

english

File:

PDF, 545 KB

english, 1997

29

Mechano-chemical formation of indomethacin β cyclodextrin inclusion compounds in powder phase roll mixtures

Yasuo Nozawa, Yoshio Morioka, Yasuyuki Sadzuka, Atsuo Miyagishima, Sadao Hirota, J.Keith Guillory

Journal:

Pharmaceutica Acta Helvetiae

Year:

1997

Language:

english

File:

PDF, 555 KB

english, 1997

30

Study on the characterization of mixed polyethyleneglycol modified liposomes containing doxorubicin

Yasuyuki Sadzuka, Akiko Nakade, Tomoko Tsuruda, Takashi Sonobe

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 506 KB

english, 2003

31

Physical properties and tissue distribution of adriamycin encapsulated in polyethyleneglycol-coated liposomes

Yasuyuki Sadzuka, Sadao Hirota

Journal:

Advanced Drug Delivery Reviews

Year:

1997

Language:

english

File:

PDF, 887 KB

english, 1997

32

Theanine and glutamate transporter inhibitors enhance the antitumor efficacy of chemotherapeutic agents

Tomomi Sugiyama, Yasuyuki Sadzuka

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2003

Language:

english

File:

PDF, 1.12 MB

english, 2003

33

Effect of cisplatin on the activities of enzymes which protect against lipid peroxidation

Yasuyuki Sadzuka, Takahiro Shoji, Yoshio Takino

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 258 KB

english, 1992

34

Protection against cisplatin-induced nephrotoxicity in the rat by inducers and an inhibitor of glutathione S-transferase

Sadzuka Yasuyuki, Shimizu Yoshihiko, Taking Yoshio, Hirota Sadao

Journal:

Biochemical Pharmacology

Year:

1994

Language:

english

File:

PDF, 653 KB

english, 1994

35

Theanine, a specific glutamate derivative in green tea, reduces the adverse reactions of doxorubicin by changing the glutathione level

Tomomi Sugiyama, Yasuyuki Sadzuka

Journal:

Year:

2004

Language:

english

File:

PDF, 255 KB

english, 2004

36

The phototoxicity of photofrin was enhanced by PEGylated liposome in vitro

Yasuyuki Sadzuka, Koji Tokutomi, Fumiaki Iwasaki, Ikumi Sugiyama, Toru Hirano, Hiroyuki Konno, Naoto Oku, Takashi Sonobe

Journal:

Year:

2006

Language:

english

File:

PDF, 225 KB

english, 2006

37

Efficacy of theanine is connected with theanine metabolism by any enzyme, not only drug metabolizing enzymes

Yasuyuki Sadzuka, Tomomi Sugiyama, Makiko Nagamine, Keizo Umegaki, Takashi Sonobe

Journal:

Food and Chemical Toxicology

Year:

2006

Language:

english

File:

PDF, 172 KB

english, 2006

38

Anserine induced advantage effects on the antitumor activity of doxorubicin

Yasuyuki Sadzuka, Takashi Sonobe

Journal:

Food and Chemical Toxicology

Year:

2007

Language:

english

File:

PDF, 221 KB

english, 2007

39

Enhancement of doxorubicin-induced antitumor activity and reduction of adverse reactions by cucurbitacin I

Yasuyuki Sadzuka, Sadahiro Fujiki, Shigeru Itai

Journal:

Food Research International

Year:

2012

Language:

english

File:

PDF, 4.99 MB

english, 2012

40

Improvement of idarubicin induced antitumor activity and bone marrow suppression by theanine, a component of tea

Yasuyuki Sadzuka, Tomomi Sugiyama, Takashi Sonobe

Journal:

Year:

2000

Language:

english

File:

PDF, 175 KB

english, 2000

41

Effect of dihydrokainate on the antitumor activity of doxorubicin

Yasuyuki Sadzuka, Yasuyo Yamashita, Tomomi Sugiyama, Takashi Sonobe

Journal:

Year:

2002

Language:

english

File:

PDF, 178 KB

english, 2002

42

Effects of administered route on tissue distribution and antitumor activity of polyethyleneglycol-coated liposomes containing adriamycin

Yasuyuki Sadzuka, Shin-ichiro Nakai, Atsuo Miyagishima, Yasuo Nozawa, Sadao Hirota

Journal:

Year:

1997

Language:

english

File:

PDF, 3.15 MB

english, 1997

43

Effect of liposomalization on the antitumor activity, side-effects and tissue distribution of CPT-11

Yasuyuki Sadzuka, Sachiyo Hirotsu, Sadao Hirota

Journal:

Year:

1998

Language:

english

File:

PDF, 310 KB

english, 1998

44

Enhancing effects of green tea components on the antitumor activity of adriamycin against M5076 ovarian sarcoma

Tomomi Sugiyama, Yasuyuki Sadzuka

Journal:

Year:

1998

Language:

english

File:

PDF, 451 KB

english, 1998

45

Does the amount of an antitumor agent entrapped in liposomes influence its tissue distribution and cell uptake?

Yasuyuki Sadzuka, Sadao Hirota

Journal:

Year:

1998

Language:

english

File:

PDF, 137 KB

english, 1998

46

Enhanced efficacy of 1-methyl-3-propyl-7-butylxanthine on the antitumor activity of doxorubicin against doxorubicin-resistant P388 leukemia

Yasuyuki Sadzuka, Tomomi Sugiyama, Hiroyuki Sawanishi, Ken-ichi Miyamoto

Journal:

Year:

1999

Language:

english

File:

PDF, 316 KB

english, 1999

47

Effective Irinotecan (CPT-11)-containing Liposomes: Intraliposomal Conversion to the Active Metabolite SN-38

Yasuyuki Sadzuka, Sachiyo Hirotsu, Sadao Hirota

Journal:

Year:

1999

Language:

english

File:

PDF, 412 KB

english, 1999

48

Effects of shear rate in roll mixing on mechanical complex formation of ibuprofen with β-cyclodextrin

Yasuo Nozawa, Kyosuke Suzuki, Yasuyuki Sadzuka, Atsuo Miyagishima, Sadao Hirota

Journal:

Pharmaceutica Acta Helvetiae

Year:

1994

Language:

english

File:

PDF, 402 KB

english, 1994

49

Increased effects of MPDAX, a novel xanthine derivative, on antitumor activity of doxorubicin

Yasuyuki Sadzuka, Tomomi Sugiyama, Hirokazu Suzuki, Hiroyuki Sawanishi, Ken-ichi Miyamoto

Journal:

Toxicology Letters

Year:

2004

Language:

english

File:

PDF, 148 KB

english, 2004

50

Phototoxicity of coproporphyrin as a novel photodynamic therapy was enhanced by liposomalization

Yasuyuki Sadzuka, Fumiaki Iwasaki, Ikumi Sugiyama, Kentaro Horiuchi, Toru Hirano, Hidechika Ozawa, Naohiro Kanayama, Naoto Oku

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 512 KB

english, 2008

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